Insights on Microbiome Targeted Therapeutics in Immunology 2021 Report – Featuring 4D Pharma, Enterome Bioscience and Takeda Pharmaceuticals Among Others – ResearchAndMarkets.com

DUBLIN–(BUSINESS WIRE)–The “Microbiome – Targeted Therapeutics in Immunology – Thematic Research” report has been added to ResearchAndMarkets.com’s offering.

The microbiome is considered the genetic material of all microorganisms existing in and on the human body. Large resident microbial communities exist in the gastrointestinal (GI) tract, skin, and respiratory tract, and an imbalance or compromised variety in these populations can contribute to immunological disorders. Emerging therapies and increasing knowledge around the microbiome are expected to help meet the unmet needs of patients across various indications in Immunology. Therapies targeting the microbiome have been termed Live Biotherapeutic Products (LBPs) by regulatory authorities and each of them aims to address disease by altering the microbiome.

23 microbiome-targeting therapeutics are currently being developed in the US and 5EU (France, Germany, Italy, Spain, UK) for GI, dermatological, and respiratory conditions. The majority of these drugs target GI indications and are in earlier stages of clinical development. Four pipeline agents are in late-stage Phase II trials: 4D Pharma’s Blautix for irritable bowel syndrome, AOBiome’s B-244 for acne vulgaris and atopic dermatitis, Evelo Biosciences’ EDP-1815 for psoriasis, and Seres Therapeutics’ SER-287 for ulcerative colitis. These drugs are expected to launch within the next five to six years.

Companies Mentioned

• 4D Pharma
• Enterome Bioscience
• Takeda Pharmaceuticals
• Seres Therapeutics
• Rebiotix
• Intralytix
• Ferring International
• Vedanta Biosciences
• BiomX
• Johnson & Johnson
• NuBiyota
• KoBioLabs
• Kaleido Biosciences
• AOBiome
• MatriSys Bioscience
• Siolta Therapeutics
• Forte Biosciences
• Naked Biome
• Evelo Biosciences

Key Questions Answered

• Which early- and late-stage microbiome-targeting pipeline therapies are in clinical development for immunology indications?
• What are the current unmet needs that microbiome therapies can address in the treatment of autoimmune, autoinflammatory, and allergic disorders? What are the opportunities for R&D?
• What is the regulatory landscape for microbiome therapies in the US and the 5EU?
• How will the field of microbiome-targeting therapy move forward in the future? What are the key M&A deals in the field?

Scope

• Overview of microbiome therapies including classification of therapy and technologies, regulatory and market access details, product & company profiles.
• Quotes from US- and 5EU-based key opinion leaders.
• Key topics covered for microbiome therapy in immunology in the US and 5EU include trends, value chain, market analysis, opportunities, challenges and unmet needs and high-value deals.
• Pipeline analysis: Comprehensive data split across different phases and indications, emerging novel trends under development, and analysis of the most promising late-stage pipeline drugs for classes of microbiome therapies.
• Analysis of the key dynamics of the microbiome-targeting therapy market. Insightful review of the key industry drivers and challenges. Deals and R&D strategies covered to highlight business opportunities.

Reasons to Buy

• Develop and design your in-licensing and out-licensing strategies, using a detailed overview of current deals and technologies to identify companies with the highest potential.
• Develop business strategies by understanding the trends shaping and driving the global microbiome-targeting therapy market.
• Drive revenues by understanding the key trends, innovative products and technologies, market segments, and companies likely to impact the global microbiome-targeting therapy market in the future.
• Design your development strategy through a review of potential novel targets or combinations across indications.
• Understand the challenges and strategies impacting the development of microbiome-targeting therapy agents in preclinical studies and clinical trials.
• Identify emerging players with potentially strong product portfolios and create effective counter-strategies to gain a competitive advantage.
• Organize your sales and marketing efforts by identifying the classes of microbiome-targeting therapy and indications that present maximum opportunities for consolidations, investments and strategic partnerships.

Key Topics Covered:

1. Preface

2. Executive Summary

3. Overview

4. Trends

5. Value Chain

6. Current Therapies

6.1. Fecal Microbiota Transplant

6.1.1. Fecal Microbiota Transplants – KOLs Perspective

6.1.2. Fecal Microbiota Transplants – Clinical Trial Mapping and Design

7. Pipeline Products

7.1. Microbiome Pipeline Products in the US and 5EU

7.2. Pipeline Overview of Microbiome-Targeting Therapies for Select Immunological Indications

7.3. Clinical Trial Mapping of the Gut Microbiome

7.3.1. Overview of Pipeline Therapies Targeting the Gut Microbiome in the US and 5EU

7.3.2. Clinical Trials for Microbiome-Targeting Agents in Gastrointestinal Indications

7.3.3. Competitive Assessment – Late-Stage Agents in Gastrointestinal Indications

7.3.3.1. Pipeline Therapies in Gastrointestinal Indications – KOLs Perspective

7.4. Clinical Trial Mapping of the Skin Microbiome

7.4.1. Overview of Pipeline Therapies Targeting the Skin Microbiome in the US and 5EU

7.4.2. Clinical Trials of Microbiome Targeting Therapies in Dermatological Indications

7.4.3. Competitive Assessment – Late-Stage Agents Targeting the Skin Microbiome

7.4.3.1. Pipeline Therapies in Dermatological Indications – KOLs Perspective

7.5. Clinical Trial Mapping of the Respiratory Microbiome

7.5.1. Overview of Pipeline Therapies Targeting the Respiratory Microbiome in the US and 5EU

7.5.2. Clinical Trials for Microbiome Targeting Therapies in Respiratory Indications

8. Market Analysis

8.1. Anticipated Key Launch Dates

8.2. Market Outlook for 4D Pharma’s Blautix

8.3. Market Outlook for Seres Therapeutics’ SER-287

8.4. Market Outlook for AOBiome’s B-244

8.5. Market Outlook for Evelo Biosciences’ EDP-1815

8.6. Top 10 Deals – Microbiome-Targeting Therapies in Select Immunology Indications

9. Regulatory and Market Access

10. Opportunities, Challenges, and Unmet Needs

11. Companies

12. Appendix

For more information about this report visit https://www.researchandmarkets.com/r/e5i5u1

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